
Monoclonal and Bispecific Anti-BCMA Antibodies in A number of Myeloma
- B-cell maturation antigen (BCMA), a member of the tumor necrosis issue receptor superfamily, is universally expressed by regular and neoplastic plasma cells and performs a essential function within the proliferation, survival and tumor development in a number of myeloma(MM). B-cell activating issue (BAFF) and a proliferation-inducing ligand (APRIL) have been acknowledged as proliferation ligands for BCMA within the bone marrow microenvironment.
- Soluble BCMA ranges within the serum correlates with illness section and tumor burden and is a predictor of progression-free survival (PFS) and general survival (OS). Not too long ago, the introduction of new monoclonal antibodies in opposition to CD38 (Daratumumab and Isatuximab) and SLAM7 (Elotuzumab) has modified the therapeutic method to MM, bettering the response fee and the time to development, each in newly recognized and refractory/relapsed sufferers.
- Among the many floor antigens on MM cells, BCMA is an acceptable goal for the design of latest antibody-based methods. Experimental approaches focusing on BCMA are at the moment being investigated and embrace antibody-drug conjugates (ADCs), bispecific antibodies (bsAbs) and genetically engineered T-cells with chimeric antigen receptors (CAR).
- On this assessment we summarize the newer findings about BCMA biologic rationale as a therapeutic goal and report the up to date outcomes of preclinical and scientific research targeted on ADCs and bsAbs focusing on BCMA.

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![]() Chicken Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Ch-96T | DL Develop | 96T | EUR 531 |
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Description: A sandwich quantitative ELISA assay kit for detection of Chicken Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Equine Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Eq-48T | DL Develop | 48T | EUR 503 |
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Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Equine Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Eq-96T | DL Develop | 96T | EUR 654 |
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Description: A sandwich quantitative ELISA assay kit for detection of Equine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Fish Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Fi-48T | DL Develop | 48T | EUR 503 |
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Description: A sandwich quantitative ELISA assay kit for detection of Fish Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates or other biological fluids. |
![]() Fish Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Fi-96T | DL Develop | 96T | EUR 654 |
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Description: A sandwich quantitative ELISA assay kit for detection of Fish Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates or other biological fluids. |
![]() Human Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Hu-48T | DL Develop | 48T | EUR 333 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Human Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Hu-96T | DL Develop | 96T | EUR 420 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Porcine Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-p-48T | DL Develop | 48T | EUR 448 |
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Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Porcine Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-p-96T | DL Develop | 96T | EUR 579 |
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Description: A sandwich quantitative ELISA assay kit for detection of Porcine Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Rabbit Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Rb-48T | DL Develop | 48T | EUR 454 |
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Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Rabbit Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Rb-96T | DL Develop | 96T | EUR 587 |
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Description: A sandwich quantitative ELISA assay kit for detection of Rabbit Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Monkey Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Si-48T | DL Develop | 48T | EUR 474 |
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Description: A sandwich quantitative ELISA assay kit for detection of Monkey Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Monkey Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Si-96T | DL Develop | 96T | EUR 614 |
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Description: A sandwich quantitative ELISA assay kit for detection of Monkey Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Bovine Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-b-48Tests | Reddot Biotech | 48 Tests | EUR 409 |
![]() Bovine Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-b-96Tests | Reddot Biotech | 96 Tests | EUR 563 |
![]() Canine Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-c-48Tests | Reddot Biotech | 48 Tests | EUR 318 |
![]() Canine Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-c-96Tests | Reddot Biotech | 96 Tests | EUR 433 |
![]() Chicken Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Ch-48Tests | Reddot Biotech | 48 Tests | EUR 422 |
![]() Chicken Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Ch-96Tests | Reddot Biotech | 96 Tests | EUR 581 |
![]() Equine Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Eq-48Tests | Reddot Biotech | 48 Tests | EUR 528 |
![]() Equine Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Eq-96Tests | Reddot Biotech | 96 Tests | EUR 733 |
![]() Fish Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Fi-48Tests | Reddot Biotech | 48 Tests | EUR 528 |
![]() Fish Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Fi-96Tests | Reddot Biotech | 96 Tests | EUR 733 |
![]() Human Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 326 |
![]() Human Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 445 |
![]() Porcine Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-p-48Tests | Reddot Biotech | 48 Tests | EUR 463 |
![]() Porcine Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-p-96Tests | Reddot Biotech | 96 Tests | EUR 640 |
![]() Rabbit Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Rb-48Tests | Reddot Biotech | 48 Tests | EUR 470 |
![]() Rabbit Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Rb-96Tests | Reddot Biotech | 96 Tests | EUR 651 |
![]() Monkey Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Si-48Tests | Reddot Biotech | 48 Tests | EUR 493 |
![]() Monkey Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Si-96Tests | Reddot Biotech | 96 Tests | EUR 683 |
![]() Bovine Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-b-48Tests | Reddot Biotech | 48 Tests | EUR 392 |
![]() Bovine Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-b-96Tests | Reddot Biotech | 96 Tests | EUR 539 |
![]() Canine Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-c-48Tests | Reddot Biotech | 48 Tests | EUR 305 |
![]() Canine Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-c-96Tests | Reddot Biotech | 96 Tests | EUR 415 |
![]() Chicken Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Ch-48Tests | Reddot Biotech | 48 Tests | EUR 404 |
![]() Chicken Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Ch-96Tests | Reddot Biotech | 96 Tests | EUR 556 |
![]() Equine Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Eq-48Tests | Reddot Biotech | 48 Tests | EUR 505 |
![]() Equine Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Eq-96Tests | Reddot Biotech | 96 Tests | EUR 700 |
![]() Human Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 313 |
![]() Human Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 426 |
![]() Porcine Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-p-48Tests | Reddot Biotech | 48 Tests | EUR 443 |
![]() Porcine Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-p-96Tests | Reddot Biotech | 96 Tests | EUR 612 |
![]() Rabbit Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Rb-48Tests | Reddot Biotech | 48 Tests | EUR 450 |
![]() Rabbit Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Rb-96Tests | Reddot Biotech | 96 Tests | EUR 622 |
![]() Monkey Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Si-48Tests | Reddot Biotech | 48 Tests | EUR 472 |
![]() Monkey Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Si-96Tests | Reddot Biotech | 96 Tests | EUR 653 |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Horse) |
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4-MAA080Eq21 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8) |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Chicken) |
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4-MAA080Ga22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8) |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human) |
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4-MAA080Hu22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8) |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human) |
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4-MAA080Hu24 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8) |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig) |
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4-MAA080Po22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8) |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig) |
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4-MAA080Po24 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8) |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig) |
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4-MAA080Po26 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8) |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Rabbit) |
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4-MAA080Rb22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rabbit Interleukin 8 (IL8) |
![]() Guinea pig Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Gu-48T | DL Develop | 48T | EUR 388 |
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Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Guinea pig Interleukin 8 (IL8) ELISA Kit |
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DLR-IL8-Gu-96T | DL Develop | 96T | EUR 496 |
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Description: A sandwich quantitative ELISA assay kit for detection of Guinea pig Interleukin 8 (IL8) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
![]() Guinea pig Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Gu-48Tests | Reddot Biotech | 48 Tests | EUR 391 |
![]() Guinea pig Interleukin 8 (IL8) ELISA Kit |
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RDR-IL8-Gu-96Tests | Reddot Biotech | 96 Tests | EUR 538 |
![]() Guinea pig Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Gu-48Tests | Reddot Biotech | 48 Tests | EUR 375 |
![]() Guinea pig Interleukin 8 (IL8) ELISA Kit |
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RD-IL8-Gu-96Tests | Reddot Biotech | 96 Tests | EUR 515 |
![]() Interleukin 8 (IL8) Antibody |
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20-abx009111 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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abx018002-100ug | Abbexa | 100 ug | EUR 342 |
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![]() Interleukin 8 (IL8) Antibody |
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abx020956-05mg | Abbexa | 0.5 mg | EUR 1080 |
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![]() Interleukin 8 (IL8) Antibody |
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abx216289-100ug | Abbexa | 100 ug | EUR 439 |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx177199 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx177201 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100960 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100961 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100962 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100963 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100964 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100965 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100966 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100967 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100969 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100970 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100971 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx100972 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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abx036426-100ug | Abbexa | 100 ug | EUR 391 |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx131832 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx131833 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx131834 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx131835 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx131836 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx131837 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx131838 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx131839 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx131840 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx137023 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx173191 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx270103 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx270152 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx270200 | Abbexa |
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![]() Interleukin 8 (IL8) Antibody |
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20-abx270201 | Abbexa |
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![]() Interleukin 8 (IL8) Monoclonal Antibody (Human, Dog) |
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4-MAA080Ca22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human, Dog Interleukin 8 (IL8) |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Horse), APC |
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4-MAA080Eq21-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with APC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Horse), Biotinylated |
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4-MAA080Eq21-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with Biotin. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Horse), Cy3 |
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4-MAA080Eq21-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with Cy3. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Horse), FITC |
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4-MAA080Eq21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with FITC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Horse), HRP |
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4-MAA080Eq21-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with HRP. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Horse), PE |
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4-MAA080Eq21-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Horse Interleukin 8 (IL8). This antibody is labeled with PE. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Chicken), APC |
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4-MAA080Ga22-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with APC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Chicken), Biotinylated |
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4-MAA080Ga22-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with Biotin. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Chicken), Cy3 |
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4-MAA080Ga22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with Cy3. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Chicken), FITC |
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4-MAA080Ga22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with FITC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Chicken), HRP |
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4-MAA080Ga22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with HRP. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Chicken), PE |
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4-MAA080Ga22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Chicken Interleukin 8 (IL8). This antibody is labeled with PE. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig) |
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4-MAA080Gu21 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8) |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Guinea pig) |
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4-MAA080Gu24 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Guinea pig Interleukin 8 (IL8) |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), APC |
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4-MAA080Hu22-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with APC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), Biotinylated |
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4-MAA080Hu22-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Biotin. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), Cy3 |
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4-MAA080Hu22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Cy3. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), FITC |
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4-MAA080Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with FITC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), HRP |
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4-MAA080Hu22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with HRP. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), PE |
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4-MAA080Hu22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with PE. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), APC |
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4-MAA080Hu24-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with APC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), Biotinylated |
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4-MAA080Hu24-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Biotin. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), Cy3 |
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4-MAA080Hu24-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with Cy3. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), FITC |
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4-MAA080Hu24-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with FITC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), HRP |
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4-MAA080Hu24-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with HRP. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Human), PE |
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4-MAA080Hu24-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Interleukin 8 (IL8). This antibody is labeled with PE. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC |
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4-MAA080Po22-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated |
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4-MAA080Po22-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig), Cy3 |
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4-MAA080Po22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Cy3. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig), FITC |
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4-MAA080Po22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with FITC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig), HRP |
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4-MAA080Po22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with HRP. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig), PE |
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4-MAA080Po22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with PE. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig), APC |
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4-MAA080Po24-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with APC. |
![]() Interleukin 8 (IL8) Monoclonal Antibody (Pig), Biotinylated |
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4-MAA080Po24-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Pig Interleukin 8 (IL8). This antibody is labeled with Biotin. |
Characterization of Variable Area Genes and Discovery of Key Recognition Websites within the Complementarity Figuring out Areas of the Anti-Thiacloprid Monoclonal Antibody
- Sequence-defined recombinant antibodies (rAbs) have emerged as alternate options to hybridoma-secreted monoclonal antibodies (mAbs) for performing immunoassays. Nevertheless, the polyploidy nature of hybridomas usually results in the coexistence of aberrant or non-specific practical variable area (VR) gene transcripts, which complicates the identification of right VR sequences.
- Herein, we launched using LC-MS/MS mixed with next-generation sequencing to characterize VR sequences in an anti-thiaclopridmAb, which was produced by a hybridoma with genetic antibody variety.
- The understanding of VR sequences was verified by the practical evaluation primarily based on the recombinant antibody (rAb) expressed by HEK293 mammalian cells. The efficiency of the rAb was much like that of the parental mAb, with IC50 values of 0.73 and 0.46 μg/L as measured by ELISAs.
- Furthermore, molecular docking evaluation revealed that Ser52 (H-CDR2), Trp98, and Trp93 (L-CDR3) residues within the complementarity figuring out areas (CDRs) of the recognized VR sequences predominantly contributed to thiacloprid-specific recognition via hydrogen bonds and the CH-Ï€ interplay.
- Via single-site-directed alanine mutagenesis, we discovered that Trp98 and Trp93 (L-CDR3) confirmed excessive affinity to thiacloprid, whereas Ser52 (H-CDR2) had an auxiliary impact on the particular binding. This research presents an environment friendly and dependable approach to decide the important thing recognition websites of hapten-specific mAbs, facilitating the development of antibody properties.
RNAemia Corresponds to Illness Severity and Antibody Response in Hospitalized COVID-19 Sufferers
Extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a worldwide well being emergency. To enhance the understanding of the systemic element of SARS-CoV-2, we investigated if viral load dynamics in plasma and respiratory samples are related to antibody response and severity of coronavirus illness 2019 (COVID-19). SARS-CoV-2 RNA was present in plasma samples from 14 (44%) out of 32 sufferers.
RNAemia was detected in 5 out of 6 deadly instances. Peak IgG values have been considerably decrease in delicate/reasonable than in extreme (0.6 (interquartile vary, IQR, 0.4-3.2) vs. 11.8 (IQR, 9.9-13.0), adjusted p = 0.003) or essential instances (11.29 (IQR, 8.3-12.0), adjusted p = 0.042).
IgG titers have been considerably related to virus Ct (Cycle threshold) worth in plasma and respiratory specimens ((ß = 0.4, 95% CI (confidence interval, 0.2; 0.5), p< 0.001 and ß = 0.5, 95% CI (0.2; 0.6), p = 0.002).
A classification as extreme or a essential case was moreover inversely related to Ct values in plasma compared to delicate/reasonable instances (ß = -3.3, 95% CI (-5.8; 0.8), p = 0.024 and ß = -4.4, 95% CI (-7.2; 1.6), p = 0.007, respectively). Primarily based on the current knowledge, our speculation is that the early stage of SARS-CoV-2 an infection is characterised by a main RNAemia, as a potential manifestation of a systemic an infection. Moreover, the viral load in plasma appears to be related to a worse illness consequence.
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RD-CT-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 677 |
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DLR-CT-c-48T | DL Develop | 48T | EUR 527 |
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Description: A sandwich quantitative ELISA assay kit for detection of Canine Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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DLR-CT-c-96T | DL Develop | 96T | EUR 688 |
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Description: A sandwich quantitative ELISA assay kit for detection of Canine Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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DLR-CT-Hu-48T | DL Develop | 48T | EUR 441 |
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Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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DLR-CT-Hu-96T | DL Develop | 96T | EUR 570 |
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Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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DLR-CT-Ra-48T | DL Develop | 48T | EUR 508 |
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Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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DLR-CT-Ra-96T | DL Develop | 96T | EUR 661 |
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Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
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RDR-CT-c-48Tests | Reddot Biotech | 48 Tests | EUR 557 |
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RDR-CT-c-96Tests | Reddot Biotech | 96 Tests | EUR 774 |
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RDR-CT-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 455 |
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RDR-CT-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 629 |
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RDR-CT-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 534 |
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RDR-CT-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 742 |
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RD-CT-c-48Tests | Reddot Biotech | 48 Tests | EUR 533 |
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RD-CT-c-96Tests | Reddot Biotech | 96 Tests | EUR 740 |
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RD-CT-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 436 |
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RD-CT-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 601 |
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RD-CT-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 511 |
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RD-CT-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 709 |
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CT12-M | Alpha Diagnostics | 100 ug | EUR 482 |
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4-MAA472Hu22 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Calcitonin (CT) |
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4-MAA472Ra21 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Calcitonin (CT) |
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CT13-M | Alpha Diagnostics | 100 ug | EUR 482 |
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4-MAA472Hu22-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with APC. |
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4-MAA472Hu22-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with Biotin. |
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4-MAA472Hu22-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with Cy3. |
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4-MAA472Hu22-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with FITC. |
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4-MAA472Hu22-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with HRP. |
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4-MAA472Hu22-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with PE. |
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4-MAA472Ra21-APC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with APC. |
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4-MAA472Ra21-Biotin | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with Biotin. |
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4-MAA472Ra21-Cy3 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with Cy3. |
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4-MAA472Ra21-FITC | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with FITC. |
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4-MAA472Ra21-HRP | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with HRP. |
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4-MAA472Ra21-PE | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with PE. |
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20-abx175651 | Abbexa |
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20-abx100227 | Abbexa |
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20-abx100228 | Abbexa |
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20-abx100230 | Abbexa |
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20-abx104916 | Abbexa |
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20-abx171510 | Abbexa |
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4-PAA472Mu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT) |
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20-abx065656 | Abbexa |
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4-MAA472Hu22-APC-Cy7 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with APC-Cy7. |
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4-MAA472Ra21-APC-Cy7 | Cloud-Clone |
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Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with APC-Cy7. |
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20-abx271724 | Abbexa |
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20-abx271988 | Abbexa |
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4-RPA472Ca01 | Cloud-Clone |
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Description: Recombinant Dog Calcitonin expressed in: E.coli |
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4-RPA472Hu01 | Cloud-Clone |
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Description: Recombinant Human Calcitonin expressed in: E.coli |
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4-RPA472Mu01 | Cloud-Clone |
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Description: Recombinant Mouse Calcitonin expressed in: E.coli |
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4-PAA472Mu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with APC. |
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4-PAA472Mu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with Biotin. |
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4-PAA472Mu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with Cy3. |
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4-PAA472Mu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with FITC. |
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4-PAA472Mu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with HRP. |
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4-PAA472Mu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with PE. |
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CSB-E05133m-24T | Cusabio | 1 plate of 24 wells | EUR 165 |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Calcitonin, CT in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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1-CSB-E05133m | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Mouse Calcitonin, CT in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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abx196301-96tests | Abbexa | 96 tests | EUR 825 |
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CEA472Mu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 4391.16 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Calcitonin (CT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
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CEA472Mu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 449.27 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Calcitonin (CT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
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CEA472Mu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 598.96 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Calcitonin (CT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
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CEA472Mu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 2395.32 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Calcitonin (CT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
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4-CEA472Mu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Mouse Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species. |
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CN-02845M1 | ChemNorm | 96T | EUR 434 |
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CN-02845M2 | ChemNorm | 48T | EUR 284 |
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EM0954 | FN Test | 96T | EUR 476.25 |
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Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml |
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GA-E0083MS-48T | GenAsia Biotech | 48T | EUR 336 |
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GA-E0083MS-96T | GenAsia Biotech | 96T | EUR 534 |
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RK02716 | Abclonal | 96 Tests | EUR 521 |
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QY-E20233 | Qayee Biotechnology | 96T | EUR 361 |
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4-PAA472Ca01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Dog Calcitonin (CT) |
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4-PAA472Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Calcitonin (CT) |
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4-PAA472Hu02 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Calcitonin (CT) |
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20-abx168025 | Abbexa |
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